Selank is a synthetic heptapeptide derived from the naturally occurring immunomodulatory peptide tuftsin. It has been studied for its role in modulating anxiety, inflammatory tone, and cognitive function through central and peripheral pathways. At Orion Biomedica, Selank is considered for individualized experimental use in neuropsychiatric and neuroimmune support protocols.
📌 Read more about the scientific studies on Selank in neuroregulation and immune modulation.
Mechanisms of Action
Selank is classified as an anxiolytic and neuroactive peptide that interacts with both the central nervous and immune systems. Experimental data suggest that Selank may:
- Reduce symptoms associated with anxiety and stress responses
- Modulate expression of key neurotransmitters (e.g., GABA, serotonin, dopamine)
- Regulate inflammatory cytokine activity in the brain and peripheral immune system
- Enhance concentration and cognitive stability under fatigue
- Act as a neuroprotective agent in states of oxidative or immune-induced stress
Selank is typically administered via intranasal delivery, enabling direct access to the central nervous system through the olfactory and trigeminal pathways. This route is non-invasive and well suited for outpatient settings.
📌 See publications on Selank’s central and immune-mediated mechanisms of action.
Individualized Therapeutic Application
At Orion Biomedica, Selank is offered in selected cases under medical evaluation. It may be considered for supportive purposes in patients with:
- Stress-related mental fatigue
- Mild to moderate symptoms of anxiety
- Immune dysregulation with neuropsychiatric features
- Difficulty concentrating or maintaining mental clarity
- Post-viral fatigue with cognitive involvement
All applications are based on a detailed clinical interview and do not replace conventional psychiatric or neurological care.
Therapeutic Fields of Research Interest and Administration Protocols
Selank has been investigated across neuropsychiatry, immunology, and cognitive neuroscience. Its dual influence on neurotransmitter balance and immune signaling makes it relevant in interdisciplinary protocols.
🔬 Selank Protocol Matrix
| Therapeutic Area | Primary Aim | Recommended Administration Route | Clinical Setting |
|---|---|---|---|
| Psychiatry | Anxiolytic support in stress or adjustment states | Intranasal spray | Outpatient neuroclinic |
| Neurocognitive Support | Focus, clarity, and fatigue modulation | Intranasal spray | Outpatient setting |
| Neuroimmune Conditions | Support in immune-linked cognitive symptoms | Intranasal spray (daily or cyclic) | Outpatient clinic |
| Post-viral Recovery | Mental fatigue and cognitive imbalance | Intranasal spray (as adjunct) | Outpatient clinic |
| Sleep and Adaptation | Modulation of stress-hormonal interactions | Intranasal spray (evening dose) | Outpatient clinic |
📌 Review academic articles exploring Selank’s neuromodulatory and anti-anxiety properties.
Clinical Framework
Peptide therapy with Selank at Orion Biomedica is:
- Used as an adjunctive and experimental support option
- Prescribed and supervised by a qualified medical professional
- Integrated only when clinically appropriate and well tolerated
- Offered with full documentation and informed consent
Selank is not used as a replacement for psychotropic medications, nor is it positioned as a cure for mental health disorders. Its role remains supportive and investigational.
Regulatory Notice
Selank is not classified as an approved medicinal product by the European Medicines Agency (EMA) or the Bulgarian Drug Agency (BDA). It is considered an experimental neuropeptide and is used only within clinically controlled settings at Orion Biomedica. Patients are fully informed of its regulatory status and therapeutic scope prior to initiation.
📞 For further information or to request a consultation, please contact Orion Biomedica.