GHK-Cu (Copper Tripeptide-1) is a naturally occurring copper-binding tripeptide with regenerative and remodeling properties. It has been studied for its role in skin repair, hair follicle activation, and tissue remodeling. At Orion Biomedica, GHK-Cu is applied as part of selected peptide protocols in aesthetic and restorative dermatology under medical supervision.
📌 Explore published studies on the cosmetic and regenerative properties of GHK-Cu.
Mechanisms of Action
GHK-Cu (Glycyl-L-histidyl-L-lysine:copper) is a biologically active peptide complex known to influence a wide range of repair-related cellular functions. Research indicates that GHK-Cu may:
- Stimulate collagen and elastin synthesis
- Promote angiogenesis and improve skin microcirculation
- Support wound healing and reduce inflammation
- Modulate oxidative stress and tissue remodeling enzymes
- Reactivate dormant hair follicles and promote scalp vitality
Administration is typically topical, using transdermal preparations (gels, creams, microneedling serums), or applied after aesthetic procedures to enhance post-treatment recovery.
📌 Learn more about how GHK-Cu supports the extracellular matrix and skin renewal.
Individualized Therapeutic Application
GHK-Cu is utilized at Orion Biomedica in cases involving cosmetic rejuvenation, scar modulation, and hair support. Based on clinical evaluation, use may be considered in:
- Non-invasive skin rejuvenation programs
- Post-laser or microneedling recovery protocols
- Scar appearance reduction and remodeling
- Cosmetic wound healing support
- Hair density stimulation in early-stage thinning
All applications are selected based on skin condition, therapeutic goals, and individual suitability.
Therapeutic Fields of Research Interest and Administration Protocols
GHK-Cu has been extensively studied in dermatology and aesthetic science for its effects on collagen regulation, tissue tone, and scalp health. At Orion Biomedica, protocols are designed to match both clinical objectives and methods of delivery.
🔬 GHK-Cu Protocol Matrix
| Therapeutic Area | Primary Aim | Recommended Administration Route | Clinical Setting |
|---|---|---|---|
| Aesthetic Dermatology | Skin tone, elasticity, and rejuvenation | Topical (cream, serum, or mask) | Outpatient aesthetic unit |
| Scar Modulation | Scar softening and remodeling | Topical (combined with microneedling or laser) | Outpatient dermatology |
| Wound Recovery | Post-procedure or cosmetic wound healing | Topical (gel or transdermal serum) | Outpatient clinic |
| Hair Restoration Support | Stimulation of hair follicles and scalp repair | Topical (serum or microneedling application) | Outpatient dermatology |
| Anti-inflammatory Skin Care | Support for inflamed or sensitive skin | Topical (low-concentration formulations) | Outpatient dermatology |
📌 View scientific reviews highlighting GHK-Cu’s role in cosmetic peptide-based interventions.
Clinical Framework
Peptide therapy with GHK-Cu at Orion Biomedica is:
- Administered under physician guidance in controlled clinical conditions
- Selected as a supportive topical intervention for tissue restoration
- Tailored to skin type, patient history, and aesthetic goals
- Used in combination with or following other skin procedures as needed
All treatments are presented as supportive care, based on scientific rationale, and not positioned as curative or pharmaceutical.
Regulatory Notice
GHK-Cu is not classified as a medicinal product by the European Medicines Agency (EMA) or the Bulgarian Drug Agency (BDA). It is used in dermatology at Orion Biomedica as a cosmetically active peptide under clinical discretion. All patients are informed of the peptide’s status and scope of use prior to therapy initiation.
📞 For further information or to request a consultation, please contact Orion Biomedica.