Fibromyalgia (FM) is a complex chronic condition characterized by widespread musculoskeletal pain, persistent fatigue, cognitive difficulties, and sleep disturbances. Although the exact cause of FM remains unknown, research suggests that nutritional imbalances, oxidative stress, and exposure to environmental toxins may contribute to its development and symptom persistence. Orion Biomedica applies an integrative approach to fibromyalgia management, combining evidence-based nutritional strategies and environmental medicine to improve quality of life and reduce symptom burden.
Nutritional Strategies
Balanced nutrition plays a central role in supporting cellular processes and reducing oxidative stress, which is frequently elevated in individuals with FM. A diet rich in antioxidants, essential vitamins, and minerals can mitigate inflammation and support neuromuscular function.
Nutrients of particular relevance include:
- Magnesium, essential for muscle relaxation and mitochondrial energy production. Deficiency may intensify fatigue and muscle discomfort.
- Selenium, a key component of antioxidant defense, helping to protect muscle tissue from inflammatory damage.
- Vitamin D, commonly found at low levels in FM, and linked to muscle function and general well-being.
- Vitamin B12, important for nerve function and cognitive clarity. Insufficiency may be associated with tingling sensations and mental fatigue.
Dietary recommendations emphasize whole foods such as fresh vegetables, oily fish, nuts, seeds, and lean proteins.
Targeted Nutritional Support
Individualized supplementation can assist in correcting underlying imbalances and restoring metabolic resilience. Supplement protocols at Orion Biomedica may include:
- Coenzyme Q10 to support mitochondrial function and energy metabolism.
- L-carnitine to enhance fatty acid transport into mitochondria and reduce muscular fatigue.
- Omega-3 fatty acids to modulate inflammation and improve joint flexibility.
- Glutathione and related antioxidants to counteract oxidative stress and promote tissue repair.
Environmental Considerations
Scientific evidence suggests a possible link between fibromyalgia and chronic exposure to toxic metals such as mercury, cadmium, and lead. These elements can disrupt the nervous system and immune regulation. In certain cases, reducing environmental exposure has been associated with clinical improvement.
To reduce environmental burden, recommendations include:
- Avoidance of personal care products and cleaning agents containing heavy metals or synthetic additives.
- Prioritization of filtered water and clean air where feasible.
- Selection of organic and low-toxin foods to limit dietary intake of pesticides and metal residues.
Complementary Therapeutic Approaches
- Low-intensity exercise (e.g., yoga, tai chi, Pilates) may support neuromuscular coordination and circulation without exacerbating symptoms.
- Sleep hygiene support, including magnesium or melatonin supplementation, may aid physical recovery and emotional stability.
- Stress reduction techniques such as mindfulness and breathwork are encouraged to modulate the physiological stress response.
Laboratory Diagnostics
A range of advanced diagnostic tests can identify contributing factors in fibromyalgia, allowing for tailored interventions. These include:
- Metal sensitivity testing (e.g., MELISA®) to evaluate delayed-type immune reactions to toxic metals such as mercury, nickel, and cadmium.
- Micronutrient status testing to assess magnesium, selenium, vitamin D, vitamin B12, and zinc levels.
- Oxidative stress markers (e.g., glutathione, malondialdehyde, SOD) to detect redox imbalances affecting muscle tissue and energy production.
- Inflammatory markers (e.g., CRP, TNF-α, IL-6) to evaluate chronic systemic inflammation potentially driving pain and fatigue.
These results contribute to a personalized care model based on metabolic, immune, and environmental parameters.
Scientific Perspective
Orion Biomedica integrates clinical experience with emerging scientific evidence to develop precision-based strategies for individuals living with fibromyalgia. The goal is to address underlying biological dysfunctions and improve daily functioning through tailored diagnostics, nutritional optimization, and toxin-reduction support.
References
Bjørklund G, Dadar M, Chirumbolo S, Aaseth J. Fibromyalgia and nutrition: therapeutic approaches for symptom management. Biomed Pharmacother. 2021;137:111365. doi:10.1016/j.biopha.2021.111365
Bjørklund G, Dadar M, Aaseth J. Delayed-type hypersensitivity to metals in connective tissue diseases and fibromyalgia. Environ Res. 2018;161:573–579. doi:10.1016/j.envres.2017.12.004
Semenova Y. Complex perspectives on CFS/ME and fibromyalgia: An Interview with Dr. G. Bjørklund. ARS Medica Tomitana. 2023;29(4):217–225. doi:10.2478/arsm-2023-0032
Stejskal V, Ockert K, Bjørklund G. Metal-induced inflammation triggers fibromyalgia in metal-allergic patients. Neuro Endocrinol Lett. 2013;34(6):559–565.
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